3-nitropropionic acid is a suicide inhibitor of
mitochondrial respiration that, upon oxidation by complex II, forms a
covalent adduct with a catalytic base arginine in the active site of
the enzyme.
J Biol Chem. 2006
Mar 3;
281(
9):
5965-72. Epub 2005 Dec 21.
PMID: 16371358 [PubMed - indexed for MEDLINE]