0 10 20 30 40
| | | | | |
Rhdbactersphaer -MSGIPHDHYEPRTGIEKWLHSRLPIVALAYDTIMIPTPRNLNWMWIWGVVLAFCLVLQI
Paracoccus -MAGIPHDHYEPKTGFERWLHRRLPIVSLVYDTLMIPTPKNLNWWWIWGIVLAFCLVLQI
Rbcapsul -MSGIPHDHYEPKTGIEKWLHDRLPIVGLVYDTIMIPTPKNLNWWWIWGIVLAFTLVLQI
Bostaurus ---------------MTNIRKSHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQI
chicken --------------MAPNIRKSHPLLKMINNSLIDLPAPSNISAWWNFGSLLAVCLMTQI
Saccharocere ----------------MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQI
:: : : . :: * * .:. * * :*.. *: **
Prim.cons. MSGIPHDHYEPKTGIEKWL2K2LPIV2LV2DTI2DIPTPSN2NWWW2WGS2LAFCLVLQI
50 60 70 80 90 100
| | | | | |
Rhdbactersphaer VTGIVLAMHYTPHVDLAFASVEHIMRNVNGGFMLRYLHANGASLFFIAVYLHIFRGLYYG
Paracoccus ATGIVLVMHYTPHVDLAFASVEHIMRDVNGGYMLRYLHANGASLFFLAVYIHIFRGLYYG
Rbcapsul VTGIVLAMHYTPHVDLAFASVEHIMRDVNGGWAMRYIHANGASLFFLAVYIHIFRGLYYG
Bostaurus LTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYG
chicken LTGLLLAMHYTADTSLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIFLHIGRGLYYG
Saccharocere VTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYG
**:.:.***:.. **:** * *:*: *: :* :******:**: :::*: :*****
Prim.cons. VTGIVLAMHYTPHVDLAF2SVEHIMRDVNGGW2LRYLHANGASLFFIAVY3HIFRGLYYG
110 120 130 140 150 160
| | | | | |
Rhdbactersphaer SYKAPREVTWIVGMLIYLAMMATAFMGYVLPWGQMSFWGATVITGLFGAIPGIGHSIQTW
Paracoccus SYKAPREVTWIVGMLIYLMMMGTAFMGYVLPWGQMSFWGATVITGLFGAIPGVGEAIQTW
Rbcapsul SYKAPREITWIVGMVIYLLMMGTAFMGYVLPWGQMSFWGATVITGLFGAIPGIGPSIQAW
Bostaurus SYT--FLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEW
chicken SYL--YKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGHTLVEW
Saccharocere SYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGATVITNLFSAIPFVGNDIVSW
** . * *::: : :.***:** :****.*******.*:.*** :* : *
Prim.cons. SYKAPREVTW2VG2IIYL2MMATAFMGYVLPWGQMSFWGATVIT2LF2AIPGIGHSI22W
170 180 190 200 210
| | | | | --------
Rhdbactersphaer LLGGPAVDNATLNRFFSLHYLLPFVIAALVAIHIWAFHSTGNNNPTGVEVRRTSKAEAQK
Paracoccus LLGGPAVDNPTLNRFFSLHYLLPFVIAALVVVHIWAFHTTGNNNPTGVEVRRGSKEEAKK
Rbcapsul LLGGPAVDNATLNRFFSLHYLLPFVIAALVAIHIWAFHTTGNNNPTGVEVRRTSKADAEK
Bostaurus IWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISS-------DV-
chicken AWGGFSVDNPTLTRFFALHFLLPFAIAGITIIHLTFLHESGSNNPLGISS-------DS-
Saccharocere LWGGFSVSNPTIQRFFALHYLVPFIIAAMVIMHLMALHIHGSSNPLGITG-------NL-
** :*.:.*: ***::*:::** * .:. :*: :* *..** *:
Prim.cons. L2GG22VDN2TLNRFF2LHYLLPFVIAALV2IH2WA2H2TG2NNPTG2EVRRTSKAEA6K
220 230 240 250 260 270
| | | | | |
Rhdbactersphaer DTVPFWPYFIIKDVFALAVVLLVFFAIVGFMPNYLGHPDNYIEANPLSTPAHIVPEWYFL
Paracoccus DTLPFWPYFVIKDLFALAVVLVVFFAIVGFMPNYLGHPDNYIEANPLVTPAHIVPEWYFL
Rbcapsul DTLPFWPYFVIKDLFALALVLLGFFAVVAYMPNYLGHPDNYVQANPLSTPAHIVPEWYFL
Bostaurus DKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFL
chicken DKIPFHPYYSFKDILGLTLMLTPFLTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFL
Saccharocere DRIPMHSYFIFKDLVTVFLFMLILALFVFYSPNTLGQPDNYIPGNPLVTPASIDPEWYLL
* :*: .*: :**:. :.: : .. : *: **.*:*: .*** **. * ****:*
Prim.cons. DTIPF2PYF2IKDLFALALVLLVFFA2V2FMPNYLGHPDNYIPANPLVTPAHIVPEWYFL
280 290 300 310
| ------------------ | | |
Rhdbactersphaer PFYAILRAFTADVWVVQIANFISFGIIDAKFFGVLAMFGAILVMALVPWLDTSPVRSGRY
Paracoccus PFYAILRAFTADVWVVMLVNWLSFGIIDAKFFGVIAMFGAILVMALVPWLDTSRVRSGQY
Rbcapsul PFYAILRAFAADVWVVILVDGLTFGIVDAKFFGVIAMFGAIAVMALAPWLDTSKVRSGAY
Bostaurus FAYAILRS------------------IPNKLGGVLALAFSILILALIPLLHTSKQRSMMF
chicken FAYAILRS------------------IPNKLGGVLALAASVLILFLIPFLHKSKQRTMTF
Saccharocere PFYAILRS------------------IPDKLLGVITMFAAILVLLVLPFTDRSVVRGNTF
*****: : *: **::: :: :: : * . * * :
Prim.cons. PFYAILR2FTADVWVV3LVN3LSFGII2AK2FGV2AMFGAILV2AL2PWLDTSKVRSGT2
320 330 340 350 360 370
| | | | | |
Rhdbactersphaer RPMFKIYFWLLAADFVILTWVGAQQTTFPYDWISLIASAYWFAYFLVILPILGAIEKPVA
Paracoccus RPLFKWWFWLLAVDFVVLMWVGAMPAEGIYPYIALAGSAYWFAYFLIILPLLGIIEKPDA
Rbcapsul RPKFRMWFWFLVLDFVVLTWVGAMPTEYPYDWISLIASTYWFAYFLVILPLLGATEKPEP
Bostaurus RPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLL
chicken RPLSQTLFWLLVANLLILTWIGSQPVEHPFIIIGQMASLSYFTILLILFPTIGTLENKML
Saccharocere KVLSKFFFFIFVFNFVLLGQIGACHVEVPYVLMGQIATFIYFAYFLIIVPVISTIENVLF
: : *: :. ::: * :*. . : :. .: :* :*::.* . *:
Prim.cons. RPL2K62FWLLVADFV2LTW2GAQPVEHPY2WIG2IASAY2FAYFL2ILP2LGTIE2PL2
380 390 400
| | |
Rhdbactersphaer PPATIEEDFNAHYSPATGGTKTVVAE
Paracoccus MPQTIEEDFNAHYGPETHPAE-----
Rbcapsul IPASIEEDFNSHYG---NPAE-----
Bostaurus KW------------------------
chicken NY------------------------
Saccharocere YIGRVNK-------------------
Prim.cons. 6PATIEEDFNAHYGP2T3PAETVVAE
Bos chick Sacchce Rb.s Parac Rb.capsul
1 -- -- -- M1 M1 M1
2 -- -- -- S2 A2 S2
3 -- -- -- G3 G3 G3
4 -- -- -- I4 I4 I4
5 -- -- -- P5 P5 P5
6 -- -- -- H6 H6 H6
7 -- -- -- D7 D7 D7
8 -- -- -- H8 H8 H8
9 -- -- -- Y9 Y9 Y9
10 -- -- -- E10 E10 E10
11 -- -- -- P11 P11 P11
12 -- -- -- R12 K12 K12
13 -- -- -- T13 T13 T13
14 -- M1 -- G14 G14 G14
15 M1 A2 -- I15 F15 I15
16 T2 P3 M1 H E16 E16 E16
17 N3 N4 A2 H K17 R17 K17
18 I4 I5 F3 H W18 W18 W18
19 R5 R6 R4 H L19 L19 L19
20 K6 K7 K5 H H20 H20 H20
21 S7 S8 S6 H S21 R21 D21
22 H8 H9 N7 R22 R22 R22
23 P9 P10 V8 H L23 L23 L23
24 L10 L11 Y9 H P24 P24 P24
25 M11 L12 L10 H I25 I25 I25
26 K12 K13 S11 H V26 V26 V26
27 I13 M14 L12 H A27 S27 G27
28 V14 I15 V13 H L28 L28 L28
29 N15 N16 N14 H A29 V29 V29
30 N16 N17 S15 H Y30 Y30 Y30
31 A17 S18 Y16 H D31 D31 D31
32 F18 L19 I17 H T32 T32 T32
33 I19 I20 I18 I33 L33 I33
34 D20 D21 D19 M34 M34 M34
35 L21 L22 S20 I35 I35 I35
36 P22 P23 P21 E P36 P36 P36
37 A23 A24 Q22 E T37 T37 T37
38 P24 P25 P23 E P38 P38 P38
39 S25 S26 S24 R39 K39 K39
40 N26 N27 S25 N40 N40 N40
41 I27 I28 I26 L41 L41 L41
42 S28 S29 N27 N42 N42 N42
43 S29 A30 Y28 W43 W43 W43
44 W30 W31 W29 M44 W44 W44
45 W31 W32 W30 W45 W45 W45
46 N32 N33 N31 I46 I46 I46
47 F33 F34 M32 W47 W47 W47
48 G34 G35 G33 G48 G48 G48 Heme Gly
49 S35 S36 S34 V49 I49 I49
Bos chick Sacchce Rb.s Parac Rb.capsul
50 L36 L37 L35 V50 V50 V50
51 L37 L38 L36 L51 L51 L51
52 G38 A39 G37 A52 A52 A52
53 I39 V40 L38 F53 F53 F53
54 C40 C41 C39 C54 C54 T54
55 L41 L42 L40 L55 L55 L55
56 I42 M43 V41 V56 V56 V56
57 L43 T44 I42 L57 L57 L57
58 Q44 Q45 Q43 Q58 Q58 Q58 Highly conserved
59 I45 I46 I44 I59 I59 I59 (heme pocket)
60 L46 L47 V45 V60 A60 V60
61 T47 T48 T46 T61 T61 T61 Walker S/T
62 G48 G49 G47 G62 G62 G62 Heme Gly
63 L49 L50 I48 I63 I63 I63
64 F50 L51 F49 V64 V64 V64
65 L51 L52 M50 L65 L65 L65
66 A52 A53 A51 A66 V66 A66
67 M53 M54 M52 M67 M67 M67
68 H54 H55 H53 H68 H68 H68
69 Y55 Y56 Y54 Y69 Y69 Y69
70 T56 T57 S55 T70 T70 T70
71 S57 A58 S56 P71 P71 P71
72 D58 D59 N57 H72 H72 H72
73 T59 T60 I58 V73 V73 V73
74 T60 S61 E59 D74 D74 D74
75 T61 L62 L60 L75 L75 L75
76 A62 A63 A61 A76 A76 A76
77 F63 F64 F62 F77 F77 F77
78 S64 S65 S63 A78 A78 A78
79 S65 S66 S64 S79 S79 S79
80 V66 V67 V65 V80 V80 V80
81 T67 A68 E66 E81 E81 E81
82 H68 H69 H67 H82 H82 H82
83 I69 T70 I68 I83 I83 I83
84 C70 C71 M69 M84 M84 M84
85 R71 R72 R70 R85 R85 R85
86 D72 N73 D71 N86 D86 D86
87 V73 V74 V72 V87 V87 V87
88 N74 Q75 H73 N88 N88 N88
89 Y75 Y76 N74 G89 G89 G89
90 G76 G77 G75 G90 G90 G90
91 W77 W78 Y76 F91 Y91 W91
92 I78 L79 I77 M92 M92 A92
93 I79 I80 L78 L93 L93 M93
94 R80 R81 R79 R94 R94 R94
95 Y81 N82 Y80 Y95 Y95 Y95
96 M82 L83 L81 L96 L96 I96
97 H83 H84 H82 H97 H97 H97
98 A84 A85 A83 A98 A98 A98
99 N85 N86 N84 N99 N99 N99
Bos chick Sacchce Rb.s Parac Rb.capsul
100 G86 G87 G85 G100 G100 G100
101 A87 A88 A86 A101 A101 A101
102 S88 S89 S87 S102 S102 S102 Highly conserved
103 M89 F90 F88 L103 L103 L103 (H-bond w PEWY W)
104 F90 F91 F89 F104 F104 F104
105 F91 F92 F90 F105 F105 F105
106 I92 I93 M91 I106 L106 L106
107 C93 C94 V92 A107 A107 A107
108 L94 I95 M93 V108 V108 V108
109 Y95 F96 F94 Y109 Y109 Y109
110 M96 L97 M95 L110 I110 I110
111 H97 H98 H96 H111 H111 H111
112 V98 I99 M97 I112 I112 I112
113 G99 G100 A98 F113 F113 F113
114 R100 R101 K99 R114 R114 R114
115 G101 G102 G100 G115 G115 G115
116 L102 L103 L101 L116 L116 L116
117 Y103 Y104 Y102 Y117 Y117 Y117
118 Y104 Y105 Y103 Y118 Y118 Y118
119 G105 G106 G104 G119 G119 G119
120 S106 S107 S105 S120 S120 S120
121 Y107 Y108 Y106 Y121 Y121 Y121
122 T108 L109 R107 K122 K122 K122
123 -- -- S108 A123 A123 A123
124 -- -- P109 P124 P124 P124
125 F109 Y110 R110 R125 R125 R125
126 L110 K111 V111 E126 E126 E126
127 E111 E112 T112 V127 V127 I127
128 T112 T113 L113 T128 T128 T128
129 W113 W114 W114 W129 W129 W129
130 N114 N115 N115 I130 I130 I130
131 I115 T116 V116 V131 V131 V131
132 G116 G117 G117 G132 G132 G132 Heme Gly
133 V117 V118 V118 M133 M133 M133
134 I118 I119 I119 L134 L134 V134
135 L119 L120 I120 I135 I135 I135
136 L120 L121 F121 Y136 Y136 Y136
137 L121 L122 I122 L137 L137 L137
138 T122 T123 L123 A138 M138 L138
139 V123 L124 T124 M139 M139 M139
140 M124 M125 I125 M140 M140 M140
141 A125 A126 A126 A141 G141 G141 A125M funi resis?
142 T126 T127 T127 T142 T142 T142 T100I atov res pneumo
143 A127 A128 A128 A143 A143 A143
144 F128 F129 F129 F144 F144 F144
145 M129 V130 L130 M145 M145 M145
146 G130 G131 G131 G146 G146 G146 Heme Gly
147 Y131 Y132 Y132 Y147 Y147 Y147
148 V132 V133 C133 V148 V148 V148
149 L133 L134 C134 L149 L149 L149
Bos chick Sacchce Rb.s Parac Rb.capsul
150 P134 P135 V135 P150 P150 P150
151 W135 W136 Y136 W151 W151 W151
152 G136 G137 G137 G152 G152 G152 ??? G137V,E uncouples? yeast
153 Q137 Q138 Q138 Q153 Q153 Q153
154 M138 M139 M139 M154 M154 M154 M129L atov-r toxop
155 S139 S140 S140 S155 S155 S155
156 F140 F141 H141 F156 F156 F156
157 W141 W142 W142 W157 W157 W157
158 G142 G143 G143 G158 G158 G158 G143A QOI-resist
159 A143 A144 A144 A159 A159 A159
160 T144 T145 T145 T160 T160 T160
161 V145 V146 V146 V161 V161 V161
162 I146 I147 I147 I162 I162 I162 I120V atov-r Pneumo
163 T147 T148 T148 T163 T163 T163 T121I atov-r Pneumo
164 N148 N149 N149 G164 G164 G164
165 L149 L150 L150 L165 L165 L165 L123F atov-r Pneumo
166 L150 F151 F151 F166 F166 F166
167 S151 S152 S152 G167 G167 G167 S125A atov-r Pneumo
168 A152 A153 A153 A168 A168 A168
169 I153 I154 I154 I169 I169 I169
170 P154 P155 P155 P170 P170 P170
171 Y155 Y156 F156 G171 G171 G171
172 I156 I157 V157 I172 V172 I172
173 G157 G158 G158 G173 G173 G173
174 T158 H159 N159 H174 E174 P174
175 N159 T160 D160 S175 A175 S175
176 L160 L161 I161 I176 I176 I176
177 V161 V162 V162 Q177 Q177 Q177
178 E162 E163 S163 T178 T178 A178
179 W163 W164 W164 W179 W179 W179
180 I164 A165 L165 L180 L180 L180
181 W165 W166 W166 L181 L181 L181
182 G166 G167 G167 G182 G182 G182
183 G167 G168 G168 G183 G183 G183
184 F168 F169 F169 P184 P184 P184
185 S169 S170 S170 A185 A185 A185
186 V170 V171 V171 V186 V186 V186
187 D171 D172 S172 D187 D187 D187
188 K172 N173 N173 N188 N188 N188
189 A173 P174 P174 A189 P189 A189
190 T174 T175 T175 T190 T190 T190
191 L175 L176 I176 L191 L191 L191
192 T176 T177 Q177 N192 N192 N192
193 R177 R178 R178 R193 R193 R193
194 F178 F179 F179 F194 F194 F194
195 F179 F180 F180 F195 F195 F195
196 A180 A181 A181 S196 S196 S196
197 F181 L182 L182 L197 L197 L197
198 H182 H183 H183 H198 H198 H198
199 F183 F184 Y184 Y199 Y199 Y199
Bos chick Sacchce Rb.s Parac Rb.capsul
200 I184 L185 L185 L200 L200 L200
201 L185 L186 V186 L201 L201 L201
202 P186 P187 P187 P202 P202 P202
203 F187 F188 F188 F203 F203 F203
204 I188 A189 I189 V204 V204 V204
205 I189 I190 I190 I205 I205 I205
206 M190 A191 A191 A206 A206 A206
207 A191 G192 A192 A207 A207 A207
208 I192 I193 M193 L208 L208 L208
209 A193 T194 V194 V209 V209 V209 A193V,T funi resis?
210 M194 I195 I195 A210 V210 A210
211 V195 I196 M196 I211 V211 I211
212 H196 H197 H197 H212 H212 H212
213 L197 L198 L198 I213 I213 I213
214 L198 T199 M199 W214 W214 W214
215 F199 F200 A200 A215 A215 A215
216 L200 L201 L201 F216 F216 F216
217 H201 H202 H202 H217 H217 H217
218 E202 E203 I203 S218 T218 T218
219 T203 S204 H204 T219 T219 T219
220 G204 G205 G205 G220 G220 G220
221 S205 S206 S206 N221 N221 N221
222 N206 N207 S207 N222 N222 N222
223 N207 N208 N208 N223 N223 N223
224 P208 P209 P209 P224 P224 P224
225 T209 L210 L210 T225 T225 T225
226 G210 G211 G211 G226 G226 G226
227 I211 I212 I212 V227 V227 V227
228 S212 S213 T213 E228 E228 E228
229 S213 S214 G214 V229 V229 V229
230 -- -- -- R230 R230 R230
231 -- -- -- R231 R231 R231
232 -- -- -- T232 G232 T232
233 -- -- -- S233 S233 S233
234 -- -- -- K234 K234 K234
235 -- -- -- A235 E235 A235
236 -- -- -- E236 E236 D236
237 D214 D215 N215 A237 A237 A237
238 V215 S216 L216 Q238 K238 E238
239 -- -- -- K239 K239 K239
240 D216 D217 D217 D240 D240 D240
241 K217 K218 R218 T241 T241 T241
242 I218 I219 I219 V242 L242 L242
243 P219 P220 P220 P243 P243 P243
244 F220 F221 M221 F244 F244 F244
245 H221 H222 H222 W245 W245 W245
246 P222 P223 S223 P246 P246 P246
247 Y223 Y224 Y224 Y247 Y247 Y247
248 Y224 Y225 F225 F248 F248 F248
249 T225 S226 I226 I249 V249 V249
Bos chick Sacchce Rb.s Parac Rb.capsul
250 I226 F227 F227 I250 I250 I250
251 K227 K228 K228 K251 K251 K251
252 D228 D229 D229 D252 D252 D252
253 I229 I230 L230 V253 L253 L253
254 L230 L231 V231 F254 F254 F254
255 G231 G232 T232 A255 A255 A255
256 A232 L233 V233 L256 L256 L256
257 L233 T234 F234 A257 A257 A257
258 L234 L235 L235 V258 V258 L258
259 L235 M236 F236 V259 V259 V259
260 I236 L237 M237 L260 L260 L260
261 L237 T238 L238 L261 V261 L261
262 A238 P239 I239 V262 V262 G262
263 L239 F240 L240 F263 F263 F263
264 M240 L241 A241 F264 F264 F264
265 L241 T242 L242 A265 A265 A265
266 L242 L243 F243 I266 I266 V266
267 V243 A244 V244 V267 V267 V267
268 L244 L245 F245 G268 G268 A268
269 F245 F246 Y246 F269 F269 Y269
270 A246 S247 S247 M270 M270 M270
271 P247 P248 P248 P271 P271 P271
272 D248 N249 N249 N272 N272 N272
273 L249 L250 T250 Y273 Y273 Y273
274 L250 L251 L251 L274 L274 L274
275 G251 G252 G252 G275 G275 G275
276 D252 D253 Q253 H276 H276 H276
277 P253 P254 P254 P277 P277 P277
278 D254 E255 D255 D278 D278 D278
279 N255 N256 N256 N279 N279 N279
280 Y256 F257 Y257 Y280 Y280 Y280
281 T257 T258 I258 I281 I281 V281
282 P258 P259 P259 E282 E282 Q282
283 A259 A260 G260 A283 A283 A283
284 N260 N261 N261 N284 N284 N284
285 P261 P262 P262 P285 P285 P285
286 L262 L263 L263 L286 L286 L286 Daldal L286Phe stabilizes c1 position?
287 N263 V264 V264 S287 V287 S287 \-mobility mutants at 286, 288
288 T264 T265 T265 T288 T288 T288 Brandt Y.l. T256M dead, unchnged ISP epr, Em
289 P265 P266 P266 P289 P289 P289 \-and Darrouzet T288S
290 P266 P267 A267 A290 A290 A290
291 H267 H268 S268 H291 H291 H291 Ser268-H-bind D255 in yeast. His 268 does not in ch, prox or dist.
292 I268 I269 I269 I292 I292 I292 \H291 Zn-binding in Rb, H291L nearly inactive (Ventrurolli)
293 K269 K270 D270 V293 V293 V293
294 P270 P271 P271 P294 P294 P294
295 E271 E272 E272 E295 E295 E295
296 W272 W273 W273 W296 W296 W296
297 Y273 Y274 Y274 Y297 Y297 Y297
298 F274 F275 L275 F298 F298 F298
299 L275 L276 L276 L299 L299 L299
Bos chick Sacchce Rb.s Parac Rb.capsul
300 F276 F277 P277 P300 P300 P300
301 A277 A278 F278 F301 F301 F301
302 Y278 Y279 Y279 Y302 Y302 Y302
303 A279 A280 A280 A303 A303 A303
304 I280 I281 I281 I304 I304 I304
305 L281 L282 L282 L305 L305 L305
306 R282 R283 R283 R306 R306 R306
307 S283 S284 S284 A307 A307 A307
308 -- -- -- F308 F308 F308
309 -- -- -- T309 T309 A309
310 -- -- -- A310 A310 A310
311 -- -- -- D311 D311 D311
312 -- -- -- V312 V312 V312
313 -- -- -- W313 W313 W313
314 -- -- -- V314 V314 V314
315 -- -- -- V315 V315 V315
316 -- -- -- Q316 M316 I316
317 -- -- -- I317 L317 L317
318 -- -- -- A318 V318 V318
319 -- -- -- N319 N319 D319
320 -- -- -- F320 W320 G320
321 -- -- -- I321 L321 L321
322 -- -- -- S322 S322 T322
323 -- -- -- F323 F323 F323
324 -- -- -- G324 G324 G324
325 -- -- -- I325 I325 I325
326 I284 I285 I285 I326 I326 V326
327 P285 P286 P286 D327 D327 D327
328 N286 N287 D287 A328 A328 A328
329 K287 K288 K288 K329 K329 K329
330 L288 L289 L289 F330 F330 F330
331 G289 G290 L290 F331 F331 F331
332 G290 G291 G291 G332 G332 G332
333 V291 V292 V292 V333 V333 V333
334 L292 L293 I293 L334 I334 I334
335 A293 A294 T294 A335 A335 A335
336 L294 L295 M295 M336 M336 M336
337 A295 A296 F296 F337 F337 F337
338 F296 A297 A297 G338 G338 G338
339 S297 S298 A298 A339 A339 A339
340 I298 V299 I299 I340 I340 I340
341 L299 L300 L300 L341 L341 A341
342 I300 I301 V301 V342 V342 V342
343 L301 L302 L302 M343 M343 M343
344 A302 F303 L303 A344 A344 A344
345 L303 L304 V304 L345 L345 L345
346 I304 I305 L305 V346 V346 A346
347 P305 P306 P306 P347 P347 P347
348 L306 F307 F307 W348 W348 W348
349 L307 L308 T308 L349 L349 L349
Bos chick Sacchce Rb.s Parac Rb.capsul
350 H308 H309 D309 D350 D350 D350
351 T309 K310 R310 T351 T351 T351
352 S310 S311 S311 S352 S352 S352
353 K311 K312 V312 P353 R353 K353
354 Q312 Q313 V313 V354 V354 V354
355 R313 R314 R314 R355 R355 R355
356 S314 T315 G315 S356 S356 S356
357 M315 M316 N316 G357 G357 G357
358 M316 T317 T317 R358 Q358 A358
359 F317 F318 F318 Y359 Y359 Y359
360 R318 R319 K319 R360 R360 R360
361 P319 P320 V320 P361 P361 P361
362 L320 L321 L321 M362 L362 K362
363 S321 S322 S322 F363 F363 F363
364 Q322 Q323 K323 K364 K364 R364
365 C323 T324 F324 I365 W365 M365 - C323 Coevolves with G:Cys45? (O.Fedrigo)
366 L324 L325 F325 Y366 W366 W366
367 F325 F326 F326 F367 F367 F367
368 W326 W327 F327 W368 W368 W368
369 A327 L328 I328 L369 L369 F369
370 L328 L329 F329 L370 L370 L370
371 V329 V330 V330 A371 A371 V371
372 A330 A331 F331 A372 V372 L372
373 D331 N332 N332 D373 D373 D373
374 L332 L333 F333 F374 F374 F374
375 L333 L334 V334 V375 V375 V375
376 T334 I335 L335 I376 V376 V376
377 L335 L336 L336 L377 L377 L377
378 T336 T337 G337 T378 M378 T378
379 W337 W338 Q338 W379 W379 W379
380 I338 I339 I339 V380 V380 V380
381 G339 G340 G340 G381 G381 G381
382 G340 S341 A341 A382 A382 A382
383 Q341 Q342 C342 Q383 M383 M383
384 P342 P343 H343 Q384 P384 P384
385 V343 V344 V344 T385 A385 T385
386 E344 E345 E345 T386 E386 E386
387 H345 H346 V346 F387 G387 Y387
388 P346 P347 P347 P388 I388 P388
389 Y347 F348 Y348 Y389 Y389 Y389
390 I348 I349 V349 D390 P390 D390
391 T349 I350 L350 W391 Y391 W391
392 I350 I351 M351 I392 I392 I392
393 G351 G352 G352 S393 A393 S393
394 Q352 Q353 Q353 L394 L394 L394
395 L353 M354 I354 I395 A395 I395
396 A354 A355 A355 A396 G396 A396
397 S355 S356 T356 S397 S397 S397
398 V356 L357 F357 A398 A398 T398
399 L357 S358 I358 Y399 Y399 Y399
Bos chick Sacchce Rb.s Parac Rb.capsul
400 Y358 Y359 Y359 W400 W400 W400
401 F359 F360 F360 F401 F401 F401
402 L360 T361 A361 A402 A402 A402
403 L361 I362 Y362 Y403 Y403 Y403
404 I362 L363 F363 F404 F404 F404
405 L363 L364 L364 L405 L405 L405
406 V364 I365 I365 V406 I406 V406
407 L365 L366 I366 I407 I407 I407
408 M366 F367 V367 L408 L408 L408
409 P367 P368 P368 P409 P409 P409
410 T368 T369 V369 I410 L410 L410
411 A369 I370 I370 L411 L411 L411
412 G370 G371 S371 G412 G412 G412
413 T371 T372 T372 A413 I413 A413
414 I372 L373 I373 I414 I414 T414
415 E373 E374 E374 E415 E415 E415
416 N374 N375 N375 K416 K416 K416
417 K375 K376 V376 P417 P417 P417
418 L376 M377 L377 V418 D418 E418
419 L377 L378 F378 A419 A419 P419
420 K378 N379 Y379 P420 M420 I420
421 W379 Y380 I380 P421 P421 P421
422 -- -- G381 A422 Q422 A422
423 -- -- R382 T423 T423 S423
424 -- -- V383 I424 I424 I424
425 -- -- N384 E425 E425 E425
426 -- -- K385 E426 E426 E426
427 -- -- -- D427 D427 D427
428 -- -- -- F428 F428 F428
429 -- -- -- N429 N429 N429
430 -- -- -- A430 A430 S430
431 -- -- -- H431 H431 H431
432 -- -- -- Y432 Y432 Y432
433 -- -- -- S433 G433 G433
434 -- -- -- P434 P434 --
435 -- -- -- A435 E435 --
436 -- -- -- T436 T436 --
437 -- -- -- G437 H437 N434
438 -- -- -- G438 P438 P435
439 -- -- -- T439 A439 A436
440 -- -- -- K440 E440 E437
441 -- -- -- T441 -- --
442 -- -- -- V442 -- --
443 -- -- -- V443 -- --
444 -- -- -- A444 -- --
445 -- -- -- E445 -- --
Bos chick Sacchce Rb.s Parac Rb.capsul
FASTA:
>Rhdbactersphaer
MSGIPHDHYEPRTGIEKWLHSRLPIVALAYDTIMIPTPRNLNWMWIWGVVLAFCLVLQI
VTGIVLAMHYTPHVDLAFASVEHIMRNVNGGFMLRYLHANGASLFFIAVYLHIFRGLYYG
SYKAPREVTWIVGMLIYLAMMATAFMGYVLPWGQMSFWGATVITGLFGAIPGIGHSIQTW
LLGGPAVDNATLNRFFSLHYLLPFVIAALVAIHIWAFHSTGNNNPTGVEVRRTSKAEAQK
DTVPFWPYFIIKDVFALAVVLLVFFAIVGFMPNYLGHPDNYIEANPLSTPAHIVPEWYFL
PFYAILRAFTADVWVVQIANFISFGIIDAKFFGVLAMFGAILVMALVPWLDTSPVRSGRY
RPMFKIYFWLLAADFVILTWVGAQQTTFPYDWISLIASAYWFAYFLVILPILGAIEKPVA
PPATIEEDFNAHYSPATGGTKTVVAE
>Paracoccus
MAGIPHDHYEPKTGFERWLHRRLPIVSLVYDTLMIPTPKNLNWWWIWGIVLAFCLVLQI
ATGIVLVMHYTPHVDLAFASVEHIMRDVNGGYMLRYLHANGASLFFLAVYIHIFRGLYYG
SYKAPREVTWIVGMLIYLMMMGTAFMGYVLPWGQMSFWGATVITGLFGAIPGVGEAIQTW
LLGGPAVDNPTLNRFFSLHYLLPFVIAALVVVHIWAFHTTGNNNPTGVEVRRGSKEEAKK
DTLPFWPYFVIKDLFALAVVLVVFFAIVGFMPNYLGHPDNYIEANPLVTPAHIVPEWYFL
PFYAILRAFTADVWVVMLVNWLSFGIIDAKFFGVIAMFGAILVMALVPWLDTSRVRSGQY
RPLFKWWFWLLAVDFVVLMWVGAMPAEGIYPYIALAGSAYWFAYFLIILPLLGIIEKPDA
MPQTIEEDFNAHYGPETHPAE-----
>Rbcapsul
MSGIPHDHYEPKTGIEKWLHDRLPIVGLVYDTIMIPTPKNLNWWWIWGIVLAFTLVLQI
VTGIVLAMHYTPHVDLAFASVEHIMRDVNGGWAMRYIHANGASLFFLAVYIHIFRGLYYG
SYKAPREITWIVGMVIYLLMMGTAFMGYVLPWGQMSFWGATVITGLFGAIPGIGPSIQAW
LLGGPAVDNATLNRFFSLHYLLPFVIAALVAIHIWAFHTTGNNNPTGVEVRRTSKADAEK
DTLPFWPYFVIKDLFALALVLLGFFAVVAYMPNYLGHPDNYVQANPLSTPAHIVPEWYFL
PFYAILRAFAADVWVVILVDGLTFGIVDAKFFGVIAMFGAIAVMALAPWLDTSKVRSGAY
RPKFRMWFWFLVLDFVVLTWVGAMPTEYPYDWISLIASTYWFAYFLVILPLLGATEKPEP
IPASIEEDFNSHYG---NPAE-----
>Bostaurus
--------------MTNIRKSHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQI
LTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYG
SYTFLET--WNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEW
IWGGFSVDKATLTRFFAFHFILPFIIMAIAMVHLLFLHETGSNNPTGISS-------DV-
DKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFL
FAYAILRS------------------IPNKLGGVLALAFSILILALIPLLHTSKQRSMMF
RPLSQCLFWALVADLLTLTWIGGQPVEHPYITIGQLASVLYFLLILVLMPTAGTIENKLL
KW------------------------
>chicken
-------------MAPNIRKSHPLLKMINNSLIDLPAPSNISAWWNFGSLLAVCLMTQI
LTGLLLAMHYTADTSLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIFLHIGRGLYYG
SYLYKET--WNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGHTLVEW
AWGGFSVDNPTLTRFFALHFLLPFAIAGITIIHLTFLHESGSNNPLGISS-------DS-
DKIPFHPYYSFKDILGLTLMLTPFLTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFL
FAYAILRS------------------IPNKLGGVLALAASVLILFLIPFLHKSKQRTMTF
RPLSQTLFWLLVANLLILTWIGSQPVEHPFIIIGQMASLSYFTILLILFPTIGTLENKML
NY------------------------
>Saccharocere
---------------MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQI
VTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYG
SYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGATVITNLFSAIPFVGNDIVSW
LWGGFSVSNPTIQRFFALHYLVPFIIAAMVIMHLMALHIHGSSNPLGITG-------NL-
DRIPMHSYFIFKDLVTVFLFMLILALFVFYSPNTLGQPDNYIPGNPLVTPASIDPEWYLL
PFYAILRS------------------IPDKLLGVITMFAAILVLLVLPFTDRSVVRGNTF
KVLSKFFFFIFVFNFVLLGQIGACHVEVPYVLMGQIATFIYFAYFLIIVPVISTIENVLF
YIGRVNK-------------------